SCRS Sites Directory

Search SCRS member sites. Discover current trials.

New Orleans Center for Clinical Research (NOCCR) Knoxville is primarily a Phase I inpatient unit with access to up to 50 beds.  It is particularly well suited for conducting First-in-Human trials as it is fully equipped, including a state-of-the-art Mortara Surveyor System and is situated within the University of Tennessee Medical Center, located in close proximity to the hospital’s ER and ICU, providing added layers of safety with code team and 24-hour critical care coverage .  Our location provides access to specialists and special patient populations, on-site, same-day electronic transfer of clinical lab results, USP pharmacy capabilities, and on-site imaging services.  Additionally, we can directly access over 900 University physicians, which allows us to collaborate with specialists in all therapeutic areas.  This Unit is well known for its ability to conduct procedurally difficult trials and to recruit special populations, including volunteers with renal and hepatic insufficiency, elderly and postmenopausal volunteers, subjects with heart failure and hypertension as well as normal healthy volunteers.  While we have all of the benefits of being located on the campus of the medical center and within the hospital, we do not have any of the encumbrances as we do not fall under the hospital IRB and we execute contracts and budgets independent of the hospital.

William B. Smith, MD, President of VRG/NOCCR, is board certified in cardiology, nephrology, internal medicine and critical care and has been an industry leader in conducting clinical research for over thirty five years.  He has led in the development of adaptive study design and assisted directly with protocol development, including FIH, SAD-MAD with POC, renal PK and others.   He has been a key consultant to several large pharmaceutical companies and assisted many Biotech’s with their clinical programs. 

Volunteer Research Group (VRG) is primarily focused on conducting later phase studies in a broad array of medical specialties.  The companies share two primary missions of equal importance: to help develop safe, advanced medical options in an ethical manner and to deliver high-quality, clean data to our sponsors.  Our ability to recruit the appropriate subjects rapidly, maintain high retention rates and produce high quality data has earned us a reputation for being one of the leading independing clinical research facilities.  

While best known for our expertise and specialization in cardiovascular, renal impairment, and in-patient special population studies, VRG/NOCCR has also conducted clinical trials in many other therapeutic areas, including:

• Cardiology/Cardiac Surgery
• Endocrinology
• Gastroenterology
• General Surgery
• Healthy Volunteers
• Infectious Disease
• Musculoskeletal & Connective Tissue Disorders
• Nephrology
• Neurology
• Nutrition
• Obesity
• Otolaryngology
• Pain Management
• Phase 1
• Psychiatry
• Pulmonary/Critical Care
• Rheumatology
• Urology
• Vaccines
• Vascular
• Women’s Health

The Alliance for Multispecialty Research (AMR) is a unique network of integrated, geographically diverse, and highly experienced Clinical Research Centers of Excellence.  Chartered as a formal organization in 194, AMR Centers of Excellence provide clinical trial services across a broad base of therapeutic areas to the pharmaceutical, biotechnology, nutrition and medical device industries.  We are proud to be part of this integrated network of sites.

To learn more about AMR's fully integrated network please visit www.amrllc.com 


Name Address Country
Alliance for Multispecialty Research, LLC (AMR, LL... PO Box 1911 Spring Hill, Tennessee 37174 United States
Web Site: www.noccr.com 


  • VRG/New Orleans Center for Clinical Research Tennessee, AMR
    William B. Smith, M.D.
    1928 Alcoa Highway, Suite 107
    Knoxville, Tennessee 37920
    United States
    Map It »
  • Last UpdatedMay 23, 2017 10:24am EDT

Demographic Data

  • Start year clinical research1985
  • Phases of clinical studiesPhase I, Phase II, Phase III, Phase IV
  • Types of studiesBiologics, Drugs, Medical Devices, Nutraceuticals, Vaccines
  • PopulationsAdult 18-64 yrs, Senior 65 yrs and over
  • # of employees involved in research30
  • Days openMonday, Tuesday, Wednesday, Thursday, Friday
  • Extended office hoursYes
  • Overnight facilitiesYes
  • Dry iceYes
  • Blinded pharmacistYes
  • Dedicated monitoring spaceYes
  • Internet access for the monitorYes
  • Onsite laboratoryYes
  • Central laboratoryYes
  • Infusion capabilityYes
  • Shipping optionsFedEx, UPS, DHL, Other
  • Contact for regulatory documentsNisha Patel
  • Regulatory phone number865-305-9100 x295
  • # of days to turn around regulatory documents5
  • Type of IRB used by this siteCentral, Local
  • How often does your local IRB meet?Every other week
  • Appropriate storage facilities for productYes
  • Able to appropriately store Schedule II drugsYes
  • # days to turn around budget and contract1 week


  • William B. Smith, MD

    VRG/New Orleans Center for Clinical Research Tennessee, AMR
    Knoxville, Tennessee